Ethanol Withdrawal-Induced Dysregulation of Neurosteroid Levels in Plasma, Cortex, and Hippocampus in Genetic Animal Models of High and Low Withdrawal

RATIONALE: Endogenous γ-aminobutyric acid(A) receptor (GABA(A)R)-active neurosteroids (e.g., allopregnanolone) regulate central nervous system excitability and many physiological functions, so fluctuations are implicated in several neuropsychiatric disorders. Pertinently, evidence supports an invers...

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Udgivet i:Psychopharmacology (Berl)
Main Authors: Jensen, Jeremiah P., Nipper, Michelle A., Helms, Melinda L., Ford, Matthew M., Crabbe, John C., Rossi, David J., Finn, Deborah A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990276/
https://ncbi.nlm.nih.gov/pubmed/28664280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4671-0
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