Genotype Differences in Sensitivity to the Anticonvulsant Effect of the Synthetic Neurosteroid Ganaxolone During Chronic Ethanol Withdrawal

Sensitivity to anticonvulsant effects of the γ-aminobutyric acid(A) receptor-active neurosteroid allopregnanolone (ALLO) during ethanol withdrawal varies across genotypes, with high sensitivity in genotypes with mild withdrawal and low sensitivity in genotypes with high withdrawal. The present studi...

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Publicado no:Neuroscience
Main Authors: Nipper, Michelle A., Jensen, Jeremiah P., Helms, Melinda L., Ford, Matthew M., Crabbe, John C., Rossi, David J., Finn, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079727/
https://ncbi.nlm.nih.gov/pubmed/30513375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.11.045
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