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The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion

Mitochondria are double‐membrane‐bound organelles that constantly change shape through membrane fusion and fission. Outer mitochondrial membrane fusion is controlled by Mitofusin, whose molecular architecture consists of an N‐terminal GTPase domain, a first heptad repeat domain (HR1), two transmembr...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Daste, Frédéric, Sauvanet, Cécile, Bavdek, Andrej, Baye, James, Pierre, Fabienne, Le Borgne, Rémi, David, Claudine, Rojo, Manuel, Fuchs, Patrick, Tareste, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989784/
https://ncbi.nlm.nih.gov/pubmed/29661855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643637
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