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The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion

Mitochondria are double‐membrane‐bound organelles that constantly change shape through membrane fusion and fission. Outer mitochondrial membrane fusion is controlled by Mitofusin, whose molecular architecture consists of an N‐terminal GTPase domain, a first heptad repeat domain (HR1), two transmembr...

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Publicado en:EMBO Rep
Autores principales: Daste, Frédéric, Sauvanet, Cécile, Bavdek, Andrej, Baye, James, Pierre, Fabienne, Le Borgne, Rémi, David, Claudine, Rojo, Manuel, Fuchs, Patrick, Tareste, David
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989784/
https://ncbi.nlm.nih.gov/pubmed/29661855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643637
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