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The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion

Mitochondria are double‐membrane‐bound organelles that constantly change shape through membrane fusion and fission. Outer mitochondrial membrane fusion is controlled by Mitofusin, whose molecular architecture consists of an N‐terminal GTPase domain, a first heptad repeat domain (HR1), two transmembr...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Daste, Frédéric, Sauvanet, Cécile, Bavdek, Andrej, Baye, James, Pierre, Fabienne, Le Borgne, Rémi, David, Claudine, Rojo, Manuel, Fuchs, Patrick, Tareste, David
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989784/
https://ncbi.nlm.nih.gov/pubmed/29661855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643637
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