PRDM4 mediates YAP‐induced cell invasion by activating leukocyte‐specific integrin β2 expression

Yes‐associated protein (YAP) is a transcriptional co‐activator and a major effector of the Hippo pathway that promotes cell proliferation and stemness, while inhibiting apoptosis. YAP plays a central role in organ size control, and its deregulation strongly promotes cancer initiation and progression...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Liu, Huan, Dai, Xiaoming, Cao, Xiaolei, Yan, Huan, Ji, Xinyan, Zhang, Haitao, Shen, Shuying, Si, Yuan, Zhang, Hailong, Chen, Jianfeng, Li, Li, Zhao, Jonathan C, Yu, Jindan, Feng, Xin‐Hua, Zhao, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989780/
https://ncbi.nlm.nih.gov/pubmed/29669796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745180
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