A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis

Organ size determination is one of the most intriguing unsolved mysteries in biology. Aberrant activation of the major effector and transcription co-activator YAP in the Hippo pathway causes drastic organ enlargement in development and underlies tumorigenesis in many human cancers. However, how robu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Res
Päätekijät: Shen, Shuying, Guo, Xiaocan, Yan, Huan, Lu, Yi, Ji, Xinyan, Li, Li, Liang, Tingbo, Zhou, Dawang, Feng, Xin-Hua, Zhao, Jonathan C, Yu, Jindan, Gong, Xing-Guo, Zhang, Lei, Zhao, Bin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559818/
https://ncbi.nlm.nih.gov/pubmed/26272168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.98
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