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A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
Organ size determination is one of the most intriguing unsolved mysteries in biology. Aberrant activation of the major effector and transcription co-activator YAP in the Hippo pathway causes drastic organ enlargement in development and underlies tumorigenesis in many human cancers. However, how robu...
Gespeichert in:
| Veröffentlicht in: | Cell Res |
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| Hauptverfasser: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4559818/ https://ncbi.nlm.nih.gov/pubmed/26272168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2015.98 |
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