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Effect of Different Divalent Cations on the Kinetics and Fidelity of RB69 DNA Polymerase
Although Mg(2+) is the cation that functions as the cofactor for the nucleotidyl transfer reaction for almost all DNA polymerases, Mn(2+) can also serve, but when it does, the degree of base discrimination exhibited by most DNA polymerases (pols) is diminished. Metal ions other than Mg(2+) or Mn(2+)...
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| Опубликовано в: : | Biochemistry |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5989577/ https://ncbi.nlm.nih.gov/pubmed/27096230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01350 |
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