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Computational modeling of methionine cycle-based metabolism and DNA methylation and the implications for anti-cancer drug response prediction

The relationship between metabolism and methylation is considered to be an important aspect of cancer development and drug efficacy. However, it remains poorly defined how to apply this aspect to improve preclinical disease characterization and clinical treatment outcome. Using available molecular i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Mengying, Saad, Christian, Le, Lien, Halfter, Kathrin, Bauer, Bernhard, Mansmann, Ulrich R., Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989406/
https://ncbi.nlm.nih.gov/pubmed/29875994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24547
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