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Computational modeling of methionine cycle-based metabolism and DNA methylation and the implications for anti-cancer drug response prediction

The relationship between metabolism and methylation is considered to be an important aspect of cancer development and drug efficacy. However, it remains poorly defined how to apply this aspect to improve preclinical disease characterization and clinical treatment outcome. Using available molecular i...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Zhang, Mengying, Saad, Christian, Le, Lien, Halfter, Kathrin, Bauer, Bernhard, Mansmann, Ulrich R., Li, Jian
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989406/
https://ncbi.nlm.nih.gov/pubmed/29875994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24547
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