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Computational modeling of methionine cycle-based metabolism and DNA methylation and the implications for anti-cancer drug response prediction
The relationship between metabolism and methylation is considered to be an important aspect of cancer development and drug efficacy. However, it remains poorly defined how to apply this aspect to improve preclinical disease characterization and clinical treatment outcome. Using available molecular i...
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| Veröffentlicht in: | Oncotarget |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5989406/ https://ncbi.nlm.nih.gov/pubmed/29875994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24547 |
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