GM-CSF targeted immunomodulation affects host response to M. tuberculosis infection

Host directed immunomodulation represents potential new adjuvant therapies in infectious diseases such as tuberculosis. Major cytokines like TNFα exert a multifold role in host control of mycobacterial infections. GM-CSF and its receptor are over-expressed during acute M. tuberculosis infection and...

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Udgivet i:Sci Rep
Main Authors: Benmerzoug, Sulayman, Marinho, Fabio Vitarelli, Rose, Stéphanie, Mackowiak, Claire, Gosset, David, Sedda, Delphine, Poisson, Emeline, Uyttenhove, Catherine, Van Snick, Jacques, Jacobs, Muazzam, Garcia, Irene, Ryffel, Bernhard, Quesniaux, Valerie F. J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988704/
https://ncbi.nlm.nih.gov/pubmed/29872095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26984-3
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