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Myeloid cell TNFR1 signaling dependent liver injury and inflammation upon BCG infection

TNF plays a critical role in mononuclear cell recruitment during acute Bacillus Calmette-Guérin (BCG) infection leading to an effective immune response with granuloma formation, but may also cause tissue injury mediated by TNFR1 or TNFR2. Here we investigated the role of myeloid and T cell specific...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chavez-Galan, Leslie, Vesin, Dominique, Blaser, Guillaume, Uysal, Husnu, Benmerzoug, Sulayman, Rose, Stéphanie, Ryffel, Bernhard, Quesniaux, Valérie F. J., Garcia, Irene
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438980/
https://ncbi.nlm.nih.gov/pubmed/30923339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41629-9
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