Transmembrane Tumor Necrosis Factor Controls Myeloid-Derived Suppressor Cell Activity via TNF Receptor 2 and Protects from Excessive Inflammation during BCG-Induced Pleurisy

Pleural tuberculosis (TB) is a form of extra-pulmonary TB observed in patients infected with Mycobacterium tuberculosis. Accumulation of myeloid-derived suppressor cells (MDSC) has been observed in animal models of TB and in human patients but their role remains to be fully elucidated. In this study...

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Publicado no:Front Immunol
Main Authors: Chavez-Galan, Leslie, Vesin, Dominique, Uysal, Husnu, Blaser, Guillaume, Benkhoucha, Mahdia, Ryffel, Bernhard, Quesniaux, Valérie F. J., Garcia, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574880/
https://ncbi.nlm.nih.gov/pubmed/28890718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00999
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