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Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF

Tumor necrosis factor (TNF) is an important cytokine for host defense against pathogens but is also associated with the development of human immunopathologies. TNF blockade effectively ameliorates many chronic inflammatory conditions but compromises host immunity to tuberculosis. The search for nove...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Olleros, Maria L., Chavez-Galan, Leslie, Segueni, Noria, Bourigault, Marie L., Vesin, Dominique, Kruglov, Andrey A., Drutskaya, Marina S., Bisig, Ruth, Ehlers, Stefan, Aly, Sahar, Walter, Kerstin, Kuprash, Dmitry V., Chouchkova, Miliana, Kozlov, Sergei V., Erard, François, Ryffel, Bernard, Quesniaux, Valérie F. J., Nedospasov, Sergei A., Garcia, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534677/
https://ncbi.nlm.nih.gov/pubmed/26123801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00743-15
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