Control of Mycobacterial Infections in Mice Expressing Human Tumor Necrosis Factor (TNF) but Not Mouse TNF

Tumor necrosis factor (TNF) is an important cytokine for host defense against pathogens but is also associated with the development of human immunopathologies. TNF blockade effectively ameliorates many chronic inflammatory conditions but compromises host immunity to tuberculosis. The search for nove...

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Udgivet i:Infect Immun
Main Authors: Olleros, Maria L., Chavez-Galan, Leslie, Segueni, Noria, Bourigault, Marie L., Vesin, Dominique, Kruglov, Andrey A., Drutskaya, Marina S., Bisig, Ruth, Ehlers, Stefan, Aly, Sahar, Walter, Kerstin, Kuprash, Dmitry V., Chouchkova, Miliana, Kozlov, Sergei V., Erard, François, Ryffel, Bernard, Quesniaux, Valérie F. J., Nedospasov, Sergei A., Garcia, Irene
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Bacterial Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534677/
https://ncbi.nlm.nih.gov/pubmed/26123801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00743-15
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