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APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats

APX3330 is a selective inhibitor of APE1/Ref-1 redox activity. In this study, we investigate the therapeutic effects and underlying mechanisms of APX3330 treatment in type one diabetes mellitus (T1DM) stroke rats. Adult male Wistar rats were induced with T1DM and subjected to transient middle cerebr...

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Detalles Bibliográficos
Publicado en:Aging Dis
Main Authors: Yan, Tao, Venkat, Poornima, Chopp, Michael, Zacharek, Alex, Yu, Peng, Ning, Ruizhuo, Qiao, Xiaoxi, Kelley, Mark R., Chen, Jieli
Formato: Artigo
Idioma:Inglês
Publicado: JKL International LLC 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988600/
https://ncbi.nlm.nih.gov/pubmed/29896433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2017.1130
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