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APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats

APX3330 is a selective inhibitor of APE1/Ref-1 redox activity. In this study, we investigate the therapeutic effects and underlying mechanisms of APX3330 treatment in type one diabetes mellitus (T1DM) stroke rats. Adult male Wistar rats were induced with T1DM and subjected to transient middle cerebr...

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Foilsithe in:Aging Dis
Main Authors: Yan, Tao, Venkat, Poornima, Chopp, Michael, Zacharek, Alex, Yu, Peng, Ning, Ruizhuo, Qiao, Xiaoxi, Kelley, Mark R., Chen, Jieli
Formáid: Artigo
Teanga:Inglês
Foilsithe: JKL International LLC 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988600/
https://ncbi.nlm.nih.gov/pubmed/29896433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2017.1130
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