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APX3330 Promotes Neurorestorative Effects after Stroke in Type One Diabetic Rats

APX3330 is a selective inhibitor of APE1/Ref-1 redox activity. In this study, we investigate the therapeutic effects and underlying mechanisms of APX3330 treatment in type one diabetes mellitus (T1DM) stroke rats. Adult male Wistar rats were induced with T1DM and subjected to transient middle cerebr...

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Bibliografiska uppgifter
I publikationen:Aging Dis
Huvudupphovsmän: Yan, Tao, Venkat, Poornima, Chopp, Michael, Zacharek, Alex, Yu, Peng, Ning, Ruizhuo, Qiao, Xiaoxi, Kelley, Mark R., Chen, Jieli
Materialtyp: Artigo
Språk:Inglês
Publicerad: JKL International LLC 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988600/
https://ncbi.nlm.nih.gov/pubmed/29896433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2017.1130
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