Proprotein convertase 1/3 inhibited macrophages: A novel therapeutic based on drone macrophages

We demonstrated here thanks to proteomic, that proprotein convertase 1/3 knockdown macrophages present all the characteristic of activated pro-inflammatory macrophages. TLR4 and TLR9 signaling pathways can be enhanced leading to the secretion of pro-inflammatory factors and antitumor factors. We can...

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Detalhes bibliográficos
Publicado no:EuPA Open Proteom
Main Authors: Duhamel, Marie, Rodet, Franck, Murgoci, Adriana, Wisztorski, Maxence, Day, Robert, Fournier, Isabelle, Salzet, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Special Section: Proceedings of the 9th Annual EuPA Congress “Proteomics - Back to the Future” (June 23 - 28, 2015, Milano, Italy)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988551/
https://ncbi.nlm.nih.gov/pubmed/29900108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euprot.2016.03.003
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