Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies

High grade gliomas are the most common brain tumors in adult. These tumors are characterized by a high infiltration in microglial cells and macrophages. The immunosuppressive tumor environment is known to orient immune cells toward a pro-tumoral and anti-inflammatory phenotype. Therefore, the curren...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Duhamel, Marie, Rose, Mélanie, Rodet, Franck, Murgoci, Adriana Natalia, Zografidou, Lea, Régnier-Vigouroux, Anne, Vanden Abeele, Fabien, Kobeissy, Firas, Nataf, Serge, Pays, Laurent, Wisztorski, Maxence, Cizkova, Dasa, Fournier, Isabelle, Salzet, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986247/
https://ncbi.nlm.nih.gov/pubmed/29531019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000443
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