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The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH(3))(2)(phenanthridine)Cl]NO(3)

A trans-ddp based monofunctional phenanthridine Pt(II) complex was synthesized and characterized. its anticancer activity was studied in vitro on a panel of human cancer cell lines and mouse intestinal cancer organoids. this complex displays significant antitumor properties, with a different spectru...

詳細記述

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書誌詳細
出版年:Chem Commun (Camb)
主要な著者: Zhou, Wen, Almeqdadi, Mohammad, Xifaras, Michael E., Riddell, Imogen A., Yilmaz, Omer H., Lippard, Stephen J.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988251/
https://ncbi.nlm.nih.gov/pubmed/29484327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc00393a
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