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Pharmacologically increasing collateral perfusion during acute stroke using a carboxyhemoglobin gas transfer agent (Sanguinate™) in spontaneously hypertensive rats

Similar to patients with chronic hypertension, spontaneously hypertensive rats (SHR) develop fast core progression during middle cerebral artery occlusion (MCAO) resulting in large final infarct volumes. We investigated the effect of Sanguinate™ (SG), a PEGylated carboxyhemoglobin (COHb) gas transfe...

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Bibliografische gegevens
Gepubliceerd in:J Cereb Blood Flow Metab
Hoofdauteurs: Cipolla, Marilyn J, Linfante, Italo, Abuchowski, Abe, Jubin, Ronald, Chan, Siu-Lung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987934/
https://ncbi.nlm.nih.gov/pubmed/28436705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17705567
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