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INHIBITION OF PAI-1 IMPROVES BRAIN COLLATERAL PERFUSION AND INJURY AFTER ACUTE ISCHEMIC STROKE IN AGED HYPERTENSIVE RATS

BACKGROUND AND PURPOSE –: Aging and hypertension, co-morbidities prevalent in the stroke population, are associated with poor collateral status and worsened stroke outcome. However, underlying mechanisms by which these conditions affect stroke outcome are not clear. We studied the role of plasminoge...

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Bibliographic Details
Published in:Stroke
Main Authors: Chan, Siu-Lung, Bishop, Nicole, Li, Zhaojin, Cipolla, Marilyn J.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202199/
https://ncbi.nlm.nih.gov/pubmed/29991657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.022056
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