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INHIBITION OF PAI-1 IMPROVES BRAIN COLLATERAL PERFUSION AND INJURY AFTER ACUTE ISCHEMIC STROKE IN AGED HYPERTENSIVE RATS

BACKGROUND AND PURPOSE –: Aging and hypertension, co-morbidities prevalent in the stroke population, are associated with poor collateral status and worsened stroke outcome. However, underlying mechanisms by which these conditions affect stroke outcome are not clear. We studied the role of plasminoge...

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發表在:Stroke
Main Authors: Chan, Siu-Lung, Bishop, Nicole, Li, Zhaojin, Cipolla, Marilyn J.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202199/
https://ncbi.nlm.nih.gov/pubmed/29991657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.022056
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