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INHIBITION OF PAI-1 IMPROVES BRAIN COLLATERAL PERFUSION AND INJURY AFTER ACUTE ISCHEMIC STROKE IN AGED HYPERTENSIVE RATS

BACKGROUND AND PURPOSE –: Aging and hypertension, co-morbidities prevalent in the stroke population, are associated with poor collateral status and worsened stroke outcome. However, underlying mechanisms by which these conditions affect stroke outcome are not clear. We studied the role of plasminoge...

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Bibliographische Detailangaben
Veröffentlicht in:Stroke
Hauptverfasser: Chan, Siu-Lung, Bishop, Nicole, Li, Zhaojin, Cipolla, Marilyn J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202199/
https://ncbi.nlm.nih.gov/pubmed/29991657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.118.022056
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