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Rapamycin induces an eNOS dependent increase in brain collateral perfusion in wistar and spontaneously hypertensive rats

BACKGROUND AND PURPOSE: Rapamycin is a clinically approved mammalian target of rapamycin inhibitor that has been shown to be neuroprotective in animal models of stroke. However, the mechanism of rapamycin-induced neuroprotection is still being explored. Our aims were to determine if rapamycin improv...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Beard, Daniel J, Li, Zhaojin, Schneider, Anna M, Couch, Yvonne, Cipolla, Marilyn J, Buchan, Alastair M
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484020/
https://ncbi.nlm.nih.gov/pubmed/32772681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.120.029781
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