Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia

Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and during central nervous system (CNS) inflammation. It was initially suggested that these engrafting cells were newly derived microglia and that irradiation was essential for engraftment to occur. However, it r...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Exp Med
Κύριοι συγγραφείς: Cronk, James C., Filiano, Anthony J., Louveau, Antoine, Marin, Ioana, Marsh, Rachel, Ji, Emily, Goldman, Dylan H., Smirnov, Igor, Geraci, Nicholas, Acton, Scott, Overall, Christopher C., Kipnis, Jonathan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Rockefeller University Press 2018
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987928/
https://ncbi.nlm.nih.gov/pubmed/29643186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180247
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