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Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury

Phagocytosis of synaptic material by microglia is critical for central nervous system development. Less well understood is this microglial function in the injured adult brain. Assay of microglial phagocytosis is challenging, because peripheral myeloid cells engraft the site of injury, which could ob...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Norris, Geoffrey T., Smirnov, Igor, Filiano, Anthony J., Shadowen, Hannah M., Cody, Kris R., Thompson, Jeremy A., Harris, Tajie H., Gaultier, Alban, Overall, Christopher C., Kipnis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028515/
https://ncbi.nlm.nih.gov/pubmed/29941548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172244
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