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Neuronal integrity and complement control synaptic material clearance by microglia after CNS injury

Phagocytosis of synaptic material by microglia is critical for central nervous system development. Less well understood is this microglial function in the injured adult brain. Assay of microglial phagocytosis is challenging, because peripheral myeloid cells engraft the site of injury, which could ob...

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Bibliografische gegevens
Gepubliceerd in:J Exp Med
Hoofdauteurs: Norris, Geoffrey T., Smirnov, Igor, Filiano, Anthony J., Shadowen, Hannah M., Cody, Kris R., Thompson, Jeremy A., Harris, Tajie H., Gaultier, Alban, Overall, Christopher C., Kipnis, Jonathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Rockefeller University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028515/
https://ncbi.nlm.nih.gov/pubmed/29941548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20172244
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