ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation

Focal adhesions anchor cells to extracellular matrix (ECM) and direct assembly of a pre-stressed actin cytoskeleton. They act as a cellular sensor and regulator, linking ECM to the nucleus. Here, we identify proteolytic turnover of the anti-adhesive proteoglycan versican as a requirement for mainten...

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Publicat a:Cell Rep
Autors principals: Mead, Timothy J., Du, Yaoyao, Nelson, Courtney M., Gueye, Ndeye-Aicha, Drazba, Judith, Dancevic, Carolyn M., Vankemmelbeke, Mireille, Buttle, David J., Apte, Suneel S.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987776/
https://ncbi.nlm.nih.gov/pubmed/29642006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.034
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