Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment

BACKGROUND: Novel therapeutic approaches are required to treat ovarian cancer and dependency on glycolysis may provide new targets for treatment. This study sought to investigate the variation of expression of molecular components (GLUT1, HKII, PKM2, LDHA) of the glycolytic pathway in ovarian cancer...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Xintaropoulou, Chrysi, Ward, Carol, Wise, Alan, Queckborner, Suzanna, Turnbull, Arran, Michie, Caroline O., Williams, Alistair R. W., Rye, Tzyvia, Gourley, Charlie, Langdon, Simon P.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987622/
https://ncbi.nlm.nih.gov/pubmed/29866066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4521-4
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