Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment

BACKGROUND: Novel therapeutic approaches are required to treat ovarian cancer and dependency on glycolysis may provide new targets for treatment. This study sought to investigate the variation of expression of molecular components (GLUT1, HKII, PKM2, LDHA) of the glycolytic pathway in ovarian cancer...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Xintaropoulou, Chrysi, Ward, Carol, Wise, Alan, Queckborner, Suzanna, Turnbull, Arran, Michie, Caroline O., Williams, Alistair R. W., Rye, Tzyvia, Gourley, Charlie, Langdon, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987622/
https://ncbi.nlm.nih.gov/pubmed/29866066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4521-4
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