A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

Many cancer cells rely on aerobic glycolysis for energy production and targeting of this pathway is a potential strategy to inhibit cancer cell growth. In this study, inhibition of five glycolysis pathway molecules (GLUT1, HKII, PFKFB3, PDHK1 and LDH) using 9 inhibitors (Phloretin, Quercetin, STF31,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xintaropoulou, Chrysi, Ward, Carol, Wise, Alan, Marston, Hugh, Turnbull, Arran, Langdon, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694858/
https://ncbi.nlm.nih.gov/pubmed/26259240
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