GLP-1 Analogue Liraglutide Enhances SP-A Expression in LPS-Induced Acute Lung Injury through the TTF-1 Signaling Pathway

The reduction of pulmonary surfactant (PS) is essential for decreased pulmonary compliance and edema in acute lung injury (ALI). Thyroid transcription factor-1 (TTF-1) plays a major role in the regulation of surfactant protein-A (SP-A), the most abundant protein component of PS. Simultaneously, the...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Zhu, Tao, Li, Changyi, Zhang, Xue, Ye, Chunyan, Tang, Shuo, Zhang, Wei, Sun, Jiayang, Huang, Niwen, Wen, Fuqiang, Wang, Daoxin, Deng, Huojin, He, Jing, Qi, Di, Deng, Wang, Yang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987313/
https://ncbi.nlm.nih.gov/pubmed/29950925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3601454
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