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Effect of renal impairment on the pharmacokinetics of the GLP-1 analogue liraglutide

AIMS: To investigate whether dose adjustment of the once-daily human glucagon-like peptide-1 analogue liraglutide is required in patients with varying stages of renal impairment. METHODS: A cohort of 30 subjects, of whom 24 had varying degrees of renal impairment and six had normal renal function, w...

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Detalhes bibliográficos
Main Authors: Jacobsen, Lisbeth V, Hindsberger, Charlotte, Robson, Richard, Zdravkovic, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810801/
https://ncbi.nlm.nih.gov/pubmed/20002084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03536.x
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