Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression

Recombinant filamentous fd bacteriophages (rfd) expressing antigenic peptides were shown to induce cell-mediated immune responses in the absence of added adjuvant, being a promising delivery system for vaccination. Here, we tested the capacity of rfd phages to protect against infection with the huma...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Gomes-Neto, João F., Sartorius, Rossella, Canto, Fábio B., Almeida, Thamyres S., Dias, André A., Barbosa, Carlos-Henrique D., Melo, Guilherme A., Oliveira, Ana Carolina, Aguiar, Pedro-Henrique N., Machado, Carlos R., de Matos Guedes, Herbert L., Santiago, Marcelo F., Nóbrega, Alberto, De Berardinis, Piergiuseppe, Bellio, Maria
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987186/
https://ncbi.nlm.nih.gov/pubmed/29896197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01173
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