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Vectorized Delivery of Alpha-GalactosylCeramide and Tumor Antigen on Filamentous Bacteriophage fd Induces Protective Immunity by Enhancing Tumor-Specific T Cell Response

We have exploited the properties of filamentous bacteriophage fd to deliver immunologically active lipids together with antigenic peptides. Filamentous bacteriophages resemble for size, capability to be permeable to blood vessels, and high density antigen expression, a nature-made nanoparticle. In a...

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Publicat a:Front Immunol
Autors principals: Sartorius, Rossella, D’Apice, Luciana, Barba, Pasquale, Cipria, Deborah, Grauso, Laura, Cutignano, Adele, De Berardinis, Piergiuseppe
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031736/
https://ncbi.nlm.nih.gov/pubmed/30002659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01496
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