Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response

Filamentous bacteriophage fd particles delivering antigenic determinants via DEC-205 (fdsc-αDEC) represent a powerful delivery system that induces CD8(+) T-cell responses even when administered in the absence of adjuvants or maturation stimuli for dendritic cells. In order to investigate the mechani...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Sartorius, Rossella, D'Apice, Luciana, Trovato, Maria, Cuccaro, Fausta, Costa, Valerio, De Leo, Maria Giovanna, Marzullo, Vincenzo Manuel, Biondo, Carmelo, D'Auria, Sabato, De Matteis, Maria Antonietta, Ciccodicola, Alfredo, De Berardinis, Piergiuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520660/
https://ncbi.nlm.nih.gov/pubmed/25888235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404525
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