A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics

Genome-wide association studies (GWASs) have successfully identified thousands of genetic variants for many complex diseases; however, these variants explain only a small fraction of the heritability. Recently, genetic association studies that leverage external transcriptome data have received much...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Su, Yu-Ru, Di, Chongzhi, Bien, Stephanie, Huang, Licai, Dong, Xinyuan, Abecasis, Goncalo, Berndt, Sonja, Bezieau, Stephane, Brenner, Hermann, Caan, Bette, Casey, Graham, Chang-Claude, Jenny, Chanock, Stephen, Chen, Sai, Connolly, Charles, Curtis, Keith, Figueiredo, Jane, Gala, Manish, Gallinger, Steven, Harrison, Tabitha, Hoffmeister, Michael, Hopper, John, Huyghe, Jeroen R., Jenkins, Mark, Joshi, Amit, Le Marchand, Loic, Newcomb, Polly, Nickerson, Deborah, Potter, John, Schoen, Robert, Slattery, Martha, White, Emily, Zanke, Brent, Peters, Ulrike, Hsu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986723/
https://ncbi.nlm.nih.gov/pubmed/29727690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.03.019
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