Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

Genome-wide association studies (GWAS) have identified many common single nucleotide polymorphisms (SNPs) associated with colorectal cancer risk. These SNPs may tag correlated variants with biological importance. Fine-mapping around GWAS loci can facilitate detection of functional candidates and add...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Du, Mengmeng, Jiao, Shuo, Bien, Stephanie A., Gala, Manish, Abecasis, Goncalo, Bezieau, Stephane, Brenner, Hermann, Butterbach, Katja, Caan, Bette J., Carlson, Christopher S., Casey, Graham, Chang-Claude, Jenny, Conti, David V., Curtis, Keith R., Duggan, David, Gallinger, Steven, Haile, Robert W., Harrison, Tabitha A., Hayes, Richard B., Hoffmeister, Michael, Hopper, John L., Hudson, Thomas J., Jenkins, Mark A., Küry, Sébastien, Le Marchand, Loic, Leal, Suzanne M., Newcomb, Polly A., Nickerson, Deborah A., Potter, John D., Schoen, Robert E., Schumacher, Fredrick R., Seminara, Daniela, Slattery, Martha L., Hsu, Li, Chan, Andrew T., White, Emily, Berndt, Sonja I., Peters, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933364/
https://ncbi.nlm.nih.gov/pubmed/27379672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157521
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