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Degradation of altered mitochondria by autophagy is impaired in Lafora disease
Lafora disease (LD) is a fatal neurodegenerative disorder caused mostly by mutations in either of two genes encoding laforin and malin. LD is characterized by accumulation of a poorly-branched form of glycogen in the cytoplasm of neurons and other cells. We previously reported dysfunctional mitochon...
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| Veröffentlicht in: | FEBS J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5986609/ https://ncbi.nlm.nih.gov/pubmed/29645350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14468 |
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