Lanean...

Degradation of altered mitochondria by autophagy is impaired in Lafora disease

Lafora disease (LD) is a fatal neurodegenerative disorder caused mostly by mutations in either of two genes encoding laforin and malin. LD is characterized by accumulation of a poorly-branched form of glycogen in the cytoplasm of neurons and other cells. We previously reported dysfunctional mitochon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS J
Egile Nagusiak: Lahuerta, Marcos, Aguado, Carmen, Sánchez-Martín, Pablo, Sanz, Pascual, Knecht, Erwin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986609/
https://ncbi.nlm.nih.gov/pubmed/29645350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14468
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