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Degradation of altered mitochondria by autophagy is impaired in Lafora disease

Lafora disease (LD) is a fatal neurodegenerative disorder caused mostly by mutations in either of two genes encoding laforin and malin. LD is characterized by accumulation of a poorly-branched form of glycogen in the cytoplasm of neurons and other cells. We previously reported dysfunctional mitochon...

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Detalles Bibliográficos
Publicado en:FEBS J
Main Authors: Lahuerta, Marcos, Aguado, Carmen, Sánchez-Martín, Pablo, Sanz, Pascual, Knecht, Erwin
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986609/
https://ncbi.nlm.nih.gov/pubmed/29645350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14468
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