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Glucose-Responsive Trehalose Hydrogel for Insulin Stabilization and Delivery()

Effective delivery of therapeutic proteins is important for many biomedical applications. Yet, the stabilization of proteins during delivery and long-term storage remains a significant challenge. Herein, we report a trehalose-based hydrogel that stabilizes insulin to elevated temperatures prior to g...

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Detalhes bibliográficos
Publicado no:Macromol Biosci
Main Authors: Lee, Juneyoung, Ko, Jeong Hoon, Mansfield, Kathryn M., Nauka, Peter C., Bat, Erhan, Maynard, Heather D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986559/
https://ncbi.nlm.nih.gov/pubmed/29665232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.201700372
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