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Trehalose Glycopolymers as Excipients for Protein Stabilization
Herein, the synthesis of four different trehalose glycopolymers and investigation of their ability to stabilize proteins to heat and lyophilization stress are described. The disaccharide, α,α-trehalose, was modified with a styrenyl acetal, methacrylate acetal, styrenyl ether, or methacrylate moiety...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973403/ https://ncbi.nlm.nih.gov/pubmed/23777473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm4003046 |
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