The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells

The CCCTC-binding factor (CTCF) is a versatile transcriptional regulator required for embryogenesis, but its function in vascular development or in diseases with a vascular component is poorly understood. Here, we found that endothelial Ctcf is essential for mouse vascular development and limits acc...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Roy, Anna R., Ahmed, Abdalla, DiStefano, Peter V., Chi, Lijun, Khyzha, Nadiya, Galjart, Niels, Wilson, Michael D., Fish, Jason E., Delgado-Olguín, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2018
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986204/
https://ncbi.nlm.nih.gov/pubmed/29610276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.814699
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