Maternal obesity persistently alters cardiac progenitor gene expression and programs adult-onset heart disease susceptibility

OBJECTIVE: Heart disease risk can be programmed by intrauterine exposure to obesity. Dysregulating key transcription factors in cardiac progenitors can cause subsequent adult-onset heart disease. In this study, we investigated the transcriptional pathways that are altered in the embryonic heart and...

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Publicado en:Mol Metab
Autores principales: Ahmed, Abdalla, Liang, Minggao, Chi, Lijun, Zhou, Yu-Qing, Sled, John G., Wilson, Michael D., Delgado-Olguín, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720025/
https://ncbi.nlm.nih.gov/pubmed/33212270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101116
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