Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature

Maintenance of vascular integrity is required for embryogenesis and organ homeostasis. However, the gene expression programs that stabilize blood vessels are poorly understood. Here, we show that the histone methyltransferase Ezh2 maintains integrity of the developing vasculature by repressing a tra...

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Библиографические подробности
Опубликовано в: :Development
Главные авторы: Delgado-Olguín, Paul, Dang, Lan T., He, Daniel, Thomas, Sean, Chi, Lijun, Sukonnik, Tatyana, Khyzha, Nadiya, Dobenecker, Marc-Werner, Fish, Jason E., Bruneau, Benoit G.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2014
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302930/
https://ncbi.nlm.nih.gov/pubmed/25359725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.112607
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