Polymeric glabrescione B nanocapsules for passive targeting of Hedgehog-dependent tumor therapy in vitro

AIM: With the purpose of delivering high doses of glabrescione B (GlaB) to solid tumors after systemic administration, long-circulating GlaB-loaded oil-cored polymeric nanocapsules (NC-GlaB) were formulated. MATERIALS & METHODS: Synthesis of GlaB and its encapsulation in nanocapsules (NCs) was p...

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Vydáno v:Nanomedicine (Lond)
Hlavní autoři: Ingallina, Cinzia, Costa, Pedro M, Ghirga, Francesca, Klippstein, Rebecca, Wang, Julie T, Berardozzi, Simone, Hodgins, Naomi, Infante, Paola, Pollard, Steven M, Botta, Bruno, Al-Jamal, Khuloud T
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5986025/
https://ncbi.nlm.nih.gov/pubmed/28322108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2016-0388
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