Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity

Insulin and IGF signaling (IIS) is a complex system that controls diverse processes including growth, development, metabolism, stress responses, and aging. Drosophila melanogaster IIS is propagated by eight Drosophila insulin-like peptides (DILPs), homologs of both mammalian insulin and IGFs, with v...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Post, Stephanie, Karashchuk, Galina, Wade, John D., Sajid, Waseem, De Meyts, Pierre, Tatar, Marc
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985746/
https://ncbi.nlm.nih.gov/pubmed/29892262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00245
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