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Total Solid-Phase Synthesis of Biologically Active Drosophila Insulin-Like Peptide 2 (DILP2)

In the fruit fly Drosophila melanogaster, there are eight insulin-like peptides (DILPs) with DILPs 1-7 interacting with a sole insulin-like receptor tyrosine kinase (DInR) while DILP8 interacts with a single G protein-coupled receptor (GPCR), Lgr3. Loss-of-function dilp mutation studies show that th...

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Detalhes bibliográficos
Publicado no:Aust J Chem
Main Authors: Lin, Feng, Hossain, Mohammed Akhter, Post, Stephanie, Karashchuk, Galina, Tatar, Marc, De Meyts, Pierre, Wade, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826605/
https://ncbi.nlm.nih.gov/pubmed/29491510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1071/CH16626
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